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Characterization of xenobiotic responsive elements upstream from the drug-metabolizing cytochrome P-450c gene: a similarity to glucocorticoid regulatory elements.

The DNA element governing the inducible expression of drug-metabolizing P-450c gene by xenobiotic treatments was investigated by gene transfer methods. A variety of dissected fragments from -844 to -1140bp region which was essential for the inducibility of P-450c gene were placed on the heterologous...

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Bibliografische gegevens
Hoofdauteurs: Fujisawa-Sehara, A, Sogawa, K, Yamane, M, Fujii-Kuriyama, Y
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1987
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC340840/
https://ncbi.nlm.nih.gov/pubmed/3588289
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