A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus.

Transcription of the drug-metabolizing cytochrome P-450c gene is induced by 3-methylcholanthrene or 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Previously, we defined two xenobiotic responsive elements (XREs) of approximately equal to 15 base pairs, both of which activate transcription in cis in res...

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Main Authors: Fujisawa-Sehara, A, Yamane, M, Fujii-Kuriyama, Y
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC281864/
https://ncbi.nlm.nih.gov/pubmed/3413062
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