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A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus.

Transcription of the drug-metabolizing cytochrome P-450c gene is induced by 3-methylcholanthrene or 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Previously, we defined two xenobiotic responsive elements (XREs) of approximately equal to 15 base pairs, both of which activate transcription in cis in res...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Fujisawa-Sehara, A, Yamane, M, Fujii-Kuriyama, Y
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1988
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281864/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3413062/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.5859
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