A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus.

Transcription of the drug-metabolizing cytochrome P-450c gene is induced by 3-methylcholanthrene or 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Previously, we defined two xenobiotic responsive elements (XREs) of approximately equal to 15 base pairs, both of which activate transcription in cis in res...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Fujisawa-Sehara, A, Yamane, M, Fujii-Kuriyama, Y
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281864/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3413062/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.5859
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!