Insulin Stimulates Mitochondrial Fusion and Function in Cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 Signaling Pathway

Insulin regulates heart metabolism through the regulation of insulin-stimulated glucose uptake. Studies have indicated that insulin can also regulate mitochondrial function. Relevant to this idea, mitochondrial function is impaired in diabetic individuals. Furthermore, the expression of Opa-1 and mi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Parra, Valentina, Verdejo, Hugo E., Iglewski, Myriam, del Campo, Andrea, Troncoso, Rodrigo, Jones, Deborah, Zhu, Yi, Kuzmicic, Jovan, Pennanen, Christian, Lopez‑Crisosto, Camila, Jaña, Fabián, Ferreira, Jorge, Noguera, Eduard, Chiong, Mario, Bernlohr, David A., Klip, Amira, Hill, Joseph A., Rothermel, Beverly A., Abel, Evan Dale, Zorzano, Antonio, Lavandero, Sergio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2014
Schlagworte:
Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868041/
https://ncbi.nlm.nih.gov/pubmed/24009260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0340
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge