Insulin Stimulates Mitochondrial Fusion and Function in Cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 Signaling Pathway

Insulin regulates heart metabolism through the regulation of insulin-stimulated glucose uptake. Studies have indicated that insulin can also regulate mitochondrial function. Relevant to this idea, mitochondrial function is impaired in diabetic individuals. Furthermore, the expression of Opa-1 and mi...

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Detaylı Bibliyografya
Asıl Yazarlar: Parra, Valentina, Verdejo, Hugo E., Iglewski, Myriam, del Campo, Andrea, Troncoso, Rodrigo, Jones, Deborah, Zhu, Yi, Kuzmicic, Jovan, Pennanen, Christian, Lopez‑Crisosto, Camila, Jaña, Fabián, Ferreira, Jorge, Noguera, Eduard, Chiong, Mario, Bernlohr, David A., Klip, Amira, Hill, Joseph A., Rothermel, Beverly A., Abel, Evan Dale, Zorzano, Antonio, Lavandero, Sergio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2014
Konular:
Metabolism
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868041/
https://ncbi.nlm.nih.gov/pubmed/24009260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0340
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