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Bisubstrate Inhibitors of Biotin Protein Ligase in Mycobacterium tuberculosis Resistant to Cyclonucleoside Formation
[Image: see text] Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis, is the leading cause of bacterial infectious disease mortality. Biotin protein ligase (BirA) globally regulates lipid metabolism in Mtb through the posttranslational biotinylation of acyl coenzyme A carboxylas...
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| Autors principals: | , , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical
Society
2013
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3867986/ https://ncbi.nlm.nih.gov/pubmed/24363833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400328a |
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