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Cationic Lipid–Nucleic Acid Complexes for Gene Delivery and Silencing: Pathways and Mechanisms for Plasmid DNA and siRNA

Motivated by the promises of gene therapy, there is a large interest in developing non-viral lipid-based vectors for therapeutic applications due to their nonimmunogenicity, low toxicity, ease of production, and the potential of transferring large pieces of DNA into cells. In fact, cationic lipid (C...

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Autori principali: Ewert, Kai K., Zidovska, Alexandra, Ahmad, Ayesha, Bouxsein, Nathan F., Evans, Heather M., McAllister, Christopher S., Samuel, Charles E., Safinya, Cyrus R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867951/
https://ncbi.nlm.nih.gov/pubmed/21504103
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