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Transitions between Distinct Compaction Regimes in Complexes of Multivalent Cationic Lipids and DNA

Cationic lipids (CLs) have found widespread use as nonviral gene carriers (vectors), including applications in clinical trials of gene therapy. However, their observed transfection efficiencies (TEs) are inferior to those of viral vectors, providing a strong incentive for a detailed understanding of...

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Autors principals: Farago, Oded, Ewert, Kai, Ahmad, Ayesha, Evans, Heather M., Grønbech-Jensen, Niels, Safinya, Cyrus R.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440430/
https://ncbi.nlm.nih.gov/pubmed/18390608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.124669
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