Transitions between Distinct Compaction Regimes in Complexes of Multivalent Cationic Lipids and DNA

Cationic lipids (CLs) have found widespread use as nonviral gene carriers (vectors), including applications in clinical trials of gene therapy. However, their observed transfection efficiencies (TEs) are inferior to those of viral vectors, providing a strong incentive for a detailed understanding of...

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Main Authors: Farago, Oded, Ewert, Kai, Ahmad, Ayesha, Evans, Heather M., Grønbech-Jensen, Niels, Safinya, Cyrus R.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2008
Teme:
Supramolecular Assemblies
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440430/
https://ncbi.nlm.nih.gov/pubmed/18390608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.124669
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