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Synthesis and Characterization of Degradable Multivalent Cationic Lipids with Disulfide-Bond Spacers for Gene Delivery

Gene therapy provides powerful new approaches to cure a large variety of diseases, which are being explored in ongoing worldwide clinical trials. To overcome the limitations of viral gene delivery systems, synthetic nonviral vectors such as cationic liposomes (CLs) are desirable. However, improvemen...

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Detalhes bibliográficos
Main Authors: Shirazi, Rahau S., Ewert, Kai K., Leal, Cecilia, Majzoub, Ramsey N., Bouxsein, Nathan F., Safinya, Cyrus R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129426/
https://ncbi.nlm.nih.gov/pubmed/21640069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.04.020
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