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Computational and Analytical Modeling of Cationic Lipid-DNA Complexes

We present a theoretical study of the physical properties of cationic lipid-DNA (CL-DNA) complexes—a promising synthetically based nonviral carrier of DNA for gene therapy. The study is based on a coarse-grained molecular model, which is used in Monte Carlo simulations of mesoscopically large system...

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Autors principals: Farago, Oded, Grønbech-Jensen, Niels
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852371/
https://ncbi.nlm.nih.gov/pubmed/17259279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.096990
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