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Cationic Lipid–Nucleic Acid Complexes for Gene Delivery and Silencing: Pathways and Mechanisms for Plasmid DNA and siRNA
Motivated by the promises of gene therapy, there is a large interest in developing non-viral lipid-based vectors for therapeutic applications due to their nonimmunogenicity, low toxicity, ease of production, and the potential of transferring large pieces of DNA into cells. In fact, cationic lipid (C...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3867951/ https://ncbi.nlm.nih.gov/pubmed/21504103 |
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