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Highly efficient gene silencing activity of siRNA embedded in a nanostructured gyroid cubic lipid matrix

RNA interference (RNAi) is an evolutionarily conserved sequence-specific post-transcriptional gene silencing pathway with wide-ranging applications in functional genomics, therapeutics, and biotechnology. Cationic liposome-small interfering RNA (CL-siRNA) complexes have emerged as vectors of choice...

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Detalhes bibliográficos
Main Authors: Leal, Cecília, Bouxsein, Nathan F., Ewert, Kai K., Safinya, Cyrus R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991473/
https://ncbi.nlm.nih.gov/pubmed/21028803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1059763
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