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Highly efficient gene silencing activity of siRNA embedded in a nanostructured gyroid cubic lipid matrix

RNA interference (RNAi) is an evolutionarily conserved sequence-specific post-transcriptional gene silencing pathway with wide-ranging applications in functional genomics, therapeutics, and biotechnology. Cationic liposome-small interfering RNA (CL-siRNA) complexes have emerged as vectors of choice...

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Bibliographische Detailangaben
Hauptverfasser: Leal, Cecília, Bouxsein, Nathan F., Ewert, Kai K., Safinya, Cyrus R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991473/
https://ncbi.nlm.nih.gov/pubmed/21028803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1059763
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