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Entropic and Electrostatic Effects on the Folding Free Energy of a Surface-Attached Biomolecule: An Experimental and Theoretical Study

Surface-tethered biomolecules play key roles in many biological processes and biotechnologies. However, while the physical consequences of such surface attachment have seen significant theoretical study, to date this issue has seen relatively little experimental investigation. In response we present...

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Autors principals: Watkins, Herschel M., Vallée-Bélisle, Alexis, Ricci, Francesco, Makarov, Dmitrii E., Plaxco, Kevin W.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866038/
https://ncbi.nlm.nih.gov/pubmed/22239220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja208436p
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