Cul3-mediated Nrf2 ubiquitination and ARE activation are dependent on the partial molar volume at position 151 of Keap1

Ítems similars

• Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3-RINGBox1 protein complex and elucidation of its quaternary structure with Keap1
  per: Small, Evan, et al.
  Publicat: (2010)
• Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress
  per: Zhang, Donna D., et al.
  Publicat: (2003)
• Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction
  per: Wang, Xiao-Jun, et al.
  Publicat: (2008)
• Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase Complex
  per: Zhang, Donna D., et al.
  Publicat: (2004)
• Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2
  per: Eggler, Aimee L., et al.
  Publicat: (2005)