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Bone morphogenic protein signalling suppresses differentiation of pluripotent cells by maintaining expression of E-Cadherin

Bone morphogenic protein (BMP) signalling contributes towards maintenance of pluripotency and favours mesodermal over neural fates upon differentiation, but the mechanisms by which BMP controls differentiation are not well understood. We report that BMP regulates differentiation by blocking downregu...

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Détails bibliographiques
Auteurs principaux: Malaguti, Mattias, Nistor, Paul A, Blin, Guillaume, Pegg, Amy, Zhou, Xinzhi, Lowell, Sally
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865744/
https://ncbi.nlm.nih.gov/pubmed/24347544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01197
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