Bone morphogenic protein signalling suppresses differentiation of pluripotent cells by maintaining expression of E-Cadherin

Bone morphogenic protein (BMP) signalling contributes towards maintenance of pluripotency and favours mesodermal over neural fates upon differentiation, but the mechanisms by which BMP controls differentiation are not well understood. We report that BMP regulates differentiation by blocking downregu...

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Hlavní autoři: Malaguti, Mattias, Nistor, Paul A, Blin, Guillaume, Pegg, Amy, Zhou, Xinzhi, Lowell, Sally
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2013
Témata:
Developmental Biology and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865744/
https://ncbi.nlm.nih.gov/pubmed/24347544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01197
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