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Bone morphogenic protein signalling suppresses differentiation of pluripotent cells by maintaining expression of E-Cadherin

Bone morphogenic protein (BMP) signalling contributes towards maintenance of pluripotency and favours mesodermal over neural fates upon differentiation, but the mechanisms by which BMP controls differentiation are not well understood. We report that BMP regulates differentiation by blocking downregu...

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Detalhes bibliográficos
Main Authors: Malaguti, Mattias, Nistor, Paul A, Blin, Guillaume, Pegg, Amy, Zhou, Xinzhi, Lowell, Sally
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865744/
https://ncbi.nlm.nih.gov/pubmed/24347544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01197
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