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Bone morphogenic protein signalling suppresses differentiation of pluripotent cells by maintaining expression of E-Cadherin

Bone morphogenic protein (BMP) signalling contributes towards maintenance of pluripotency and favours mesodermal over neural fates upon differentiation, but the mechanisms by which BMP controls differentiation are not well understood. We report that BMP regulates differentiation by blocking downregu...

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Bibliografiske detaljer
Main Authors: Malaguti, Mattias, Nistor, Paul A, Blin, Guillaume, Pegg, Amy, Zhou, Xinzhi, Lowell, Sally
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865744/
https://ncbi.nlm.nih.gov/pubmed/24347544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01197
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