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Geometrical confinement controls the asymmetric patterning of brachyury in cultures of pluripotent cells

Diffusible signals are known to orchestrate patterning during embryogenesis, yet diffusion is sensitive to noise. The fact that embryogenesis is remarkably robust suggests that additional layers of regulation reinforce patterning. Here, we demonstrate that geometrical confinement orchestrates the sp...

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Библиографические подробности
Опубликовано в: :Development
Главные авторы: Blin, Guillaume, Wisniewski, Darren, Picart, Catherine, Thery, Manuel, Puceat, Michel, Lowell, Sally
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists Ltd 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176930/
https://ncbi.nlm.nih.gov/pubmed/30115626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.166025
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