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Geometrical confinement controls the asymmetric patterning of brachyury in cultures of pluripotent cells

Diffusible signals are known to orchestrate patterning during embryogenesis, yet diffusion is sensitive to noise. The fact that embryogenesis is remarkably robust suggests that additional layers of regulation reinforce patterning. Here, we demonstrate that geometrical confinement orchestrates the sp...

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Détails bibliographiques
Publié dans:Development
Auteurs principaux: Blin, Guillaume, Wisniewski, Darren, Picart, Catherine, Thery, Manuel, Puceat, Michel, Lowell, Sally
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176930/
https://ncbi.nlm.nih.gov/pubmed/30115626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.166025
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