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pH sensing and regulation in cancer

Cells maintain intracellular pH (pH(i)) within a narrow range (7.1–7.2) by controlling membrane proton pumps and transporters whose activity is set by intra-cytoplasmic pH sensors. These sensors have the ability to recognize and induce cellular responses to maintain the pH(i), often at the expense o...

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Detalhes bibliográficos
Main Authors: Damaghi, Mehdi, Wojtkowiak, Jonathan W., Gillies, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865727/
https://ncbi.nlm.nih.gov/pubmed/24381558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00370
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