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Drug resistance and cellular adaptation to tumor acidic pH microenvironment

Despite advances in developing novel therapeutic strategies, a major factor underlying cancer related death remains resistance to therapy. In addition to biochemical resistance, mediated by xenobiotic transporters or binding site mutations, resistance can be physiological; emerging as a consequence...

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Hlavní autoři: Wojtkowiak, Jonathan W., Verduzco, Daniel, Schramm, Karla J., Gillies, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230683/
https://ncbi.nlm.nih.gov/pubmed/21981633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200292c
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