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Drug resistance and cellular adaptation to tumor acidic pH microenvironment
Despite advances in developing novel therapeutic strategies, a major factor underlying cancer related death remains resistance to therapy. In addition to biochemical resistance, mediated by xenobiotic transporters or binding site mutations, resistance can be physiological; emerging as a consequence...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230683/ https://ncbi.nlm.nih.gov/pubmed/21981633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200292c |
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