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Inducing host protection in pneumococcal sepsis by preactivation of the Ashwell-Morell receptor
The endocytic Ashwell-Morell receptor (AMR) of hepatocytes detects pathogen remodeling of host glycoproteins by neuraminidase in the bloodstream and mitigates the lethal coagulopathy of sepsis. We have investigated the mechanism of host protection by the AMR during the onset of sepsis and in respons...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3864324/ https://ncbi.nlm.nih.gov/pubmed/24284176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313905110 |
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