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The Ashwell receptor mitigates the lethal coagulopathy of sepsis

The Ashwell receptor, the major lectin of hepatocytes, rapidly clears from blood circulation glycoproteins bearing glycan ligands that include galactose and N-acetylgalactosamine. This asialoglycoprotein receptor activity remains a key factor in the development and administration of glycoprotein pha...

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Detalhes bibliográficos
Main Authors: Grewal, Prabhjit K, Uchiyama, Satoshi, Ditto, David, Varki, Nissi, Le, Dzung T, Nizet, Victor, Marth, Jamey D
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853759/
https://ncbi.nlm.nih.gov/pubmed/18488037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1760
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