Tolerance develops to the antiallodynic effects of the peripherally acting opioid loperamide hydrochloride in nerve-injured rats

Peripherally acting opioids are potentially attractive drugs for the clinical management of certain chronic pain states due to the lack of centrally mediated adverse effects. However, it remains unclear whether tolerance develops to peripheral opioid analgesic effects under neuropathic pain conditio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: He, Shao-Qiu, Yang, Fei, Perez, Federico M., Xu, Qian, Shechter, Ronen, Cheong, Yong-Kwan, Carteret, Alene F., Dong, Xinzhong, Sweitzer, Sarah M., Raja, Srinivasa N., Guan, Yun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863910/
https://ncbi.nlm.nih.gov/pubmed/23880055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2013.07.023
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