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A partial L5 spinal nerve ligation induces a limited prolongation of mechanical allodynia in rats: an efficient model for studying mechanisms of neuropathic pain

The relationship between pain severity and the extent of injury to a peripheral nerve remains elusive. In this study, we compared the pain behavior resulting from partial (1/3–1/2 thickness) and full L5 spinal nerve ligation (SNL) in rats. The decrease in paw withdrawal threshold (PWT) to mechanical...

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Autori principali: Guan, Yun, Yuan, Frank, Carteret, Alene F., Raja, Srinivasa N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828364/
https://ncbi.nlm.nih.gov/pubmed/20067820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.01.006
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