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R-flurbiprofen improves tau, but not Aß pathology in a triple transgenic model of Alzheimer's disease
We have previously reported that chronic ibuprofen treatment improves cognition and decreases intracellular Aß and phosphorylated-tau levels in 3xTg-AD mice. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that independently of its anti-inflammatory effects has anti-amyloidogenic activit...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3863610/ https://ncbi.nlm.nih.gov/pubmed/24161403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2013.10.025 |
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