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The effects of aging, housing and ibuprofen treatment on brain neurochemistry in a triple transgene Alzheimer’s disease mouse model using magnetic resonance spectroscopy and imaging

We investigated a triple transgene Alzheimer’s disease (AD) mouse model that recapitulates many of the neurochemical, anatomic, pathologic and behavioral defects seen in human AD. We studied the mice as a function of age and brain region and investigated potential therapy with the non-steroidal anti...

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Dades bibliogràfiques
Publicat a:Brain Res
Autors principals: Choi, Ji-Kyung, Carreras, Isabel, Aytan, Nur, Jenkins-Sahlin, Eric, Dedeoglu, Alpaslan, Jenkins, Bruce G.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274938/
https://ncbi.nlm.nih.gov/pubmed/25301691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2014.09.067
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