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Survivin-3B promotes chemoresistance and immune escape by inhibiting caspase-8 and -6 in cancer cells

Survivin-3B (S-3B), an alternative splice isoform of survivin, plays a key role in tumorigenesis. S-3B promotes the escape of malignant cells from immune recognition by blocking the cytotoxicity of natural killer (NK) cells. Such an effect reflects the ability of S-3B to interfere with the assembly...

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Detalhes bibliográficos
Main Authors: Végran, Frédérique, Boidot, Romain
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862639/
https://ncbi.nlm.nih.gov/pubmed/24353917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26328
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