Targeting caspase-6 and caspase-8 to promote neuronal survival following ischemic stroke

Previous studies show that caspase-6 and caspase-8 are involved in neuronal apoptosis and regenerative failure after trauma of the adult central nervous system (CNS). In this study, we evaluated whether caspase-6 or -8 inhibitors can reduce cerebral or retinal injury after ischemia. Cerebral infarct...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Shabanzadeh, A P, D'Onofrio, P M, Monnier, P P, Koeberle, P D
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670918/
https://ncbi.nlm.nih.gov/pubmed/26539914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.272
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