Uncoupling Neogenin association with lipid rafts promotes neuronal survival and functional recovery after stroke

The dependence receptor Neogenin and its ligand, the repulsive guidance molecule a (RGMa), regulate apoptosis and axonal growth in the developing and the adult central nervous system (CNS). Here, we show that this pathway has also a critical role in neuronal death following stroke, and that providin...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Shabanzadeh, A P, Tassew, N G, Szydlowska, K, Tymianski, M, Banerjee, P, Vigouroux, R J, Eubanks, J H, Huang, L, Geraerts, M, Koeberle, P D, Mueller, B K, Monnier, P P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669689/
https://ncbi.nlm.nih.gov/pubmed/25950474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.109
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