Involvement of Caspase-6 and Caspase-8 in Neuronal Apoptosis and the Regenerative Failure of Injured Retinal Ganglion Cells

To promote functional recovery after CNS injuries, it is crucial to develop strategies that enhance both neuronal survival and regeneration. Here, we report that caspase-6 is upregulated in injured retinal ganglion cells and that its inhibition promotes both survival and regeneration in these adult...

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Publicado en:J Neurosci
Autores principales: Monnier, Philippe P., D'Onofrio, Philippe M., Magharious, Mark, Hollander, Adam C., Tassew, Nardos, Szydlowska, Kinga, Tymianski, Michael, Koeberle, Paulo D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2011
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622648/
https://ncbi.nlm.nih.gov/pubmed/21775595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0148-11.2011
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