Neuronal Injury External to the Retina Rapidly Activates Retinal Glia, Followed by Elevation of Markers for Cell Cycle Re-Entry and Death in Retinal Ganglion Cells

Retinal ganglion cells (RGCs) are neurons that relay visual signals from the retina to the brain. The RGC cell bodies reside in the retina and their fibers form the optic nerve. Full transection (axotomy) of the optic nerve is an extra-retinal injury model of RGC degeneration. Optic nerve transectio...

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Main Authors: Galan, Alba, Dergham, Pauline, Escoll, Pedro, de-la-Hera, Antonio, D'Onofrio, Philippe M., Magharious, Mark M., Koeberle, Paulo D., Frade, José María, Saragovi, H. Uri
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077807/
https://ncbi.nlm.nih.gov/pubmed/24983470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101349
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