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Somatic tetraploidy in specific chick retinal ganglion cells induced by nerve growth factor

A subset of neurons in the normal vertebrate nervous system contains double the normal amount of DNA in their nuclei. These neurons are all thought to derive from aberrant mitoses in neuronal precursor cells. Here we show that endogenous NGF induces DNA replication in a subpopulation of differentiat...

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Detalles Bibliográficos
Main Authors: Morillo, Sandra M., Escoll, Pedro, de la Hera, Antonio, Frade, José M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806721/
https://ncbi.nlm.nih.gov/pubmed/20018664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906121107
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