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RAD6 promotes chemoresistance in ovarian cancer

Mortality in ovarian cancer is predominantly due to acquired chemoresistance and tumor recurrence. UBIQUITIN CONJUGATING ENZYME E2 or RAD6 expression increases in cell lines and patient tumors in response to platinum-based chemotherapy and promotes both activation of DNA damage response pathways and...

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Détails bibliographiques
Publié dans:Mol Cell Oncol
Auteurs principaux: Clark, David W., Mani, Chinnadurai, Palle, Komaraiah
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791863/
https://ncbi.nlm.nih.gov/pubmed/29404391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1392403
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