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RAD6 promotes chemoresistance in ovarian cancer

Mortality in ovarian cancer is predominantly due to acquired chemoresistance and tumor recurrence. UBIQUITIN CONJUGATING ENZYME E2 or RAD6 expression increases in cell lines and patient tumors in response to platinum-based chemotherapy and promotes both activation of DNA damage response pathways and...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Clark, David W., Mani, Chinnadurai, Palle, Komaraiah
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791863/
https://ncbi.nlm.nih.gov/pubmed/29404391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1392403
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