RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance

Ovarian cancer is the most deadly gynecological cancer and unlike most other neoplasms, survival rates for ovarian cancer have not significantly improved in recent decades. We show that RAD6, an ubiquitin conjugating enzyme is significantly overexpressed in ovarian tumors and its expression increase...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Somasagara, Ranganatha R., Spencer, Sebastian M., Tripathi, Kaushlendra, Clark, David W., Mani, Chinnadurai, da Silva, Luciana Madeira, Scalici, Jennifer, Kothayer, Hend, Westwell, Andrew D., Rocconi, Rodney P., Palle, Komaraiah
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709226/
https://ncbi.nlm.nih.gov/pubmed/28806395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.279
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados