Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA topoisomerase 1 inhibition

af Palle, Komaraiah, Vaziri, Cyrus
Udgivet 2011

Aldehyde dehydrogenases in cancer stem cells: potential as therapeutic targets

af Clark, David W., Palle, Komaraiah
Udgivet i Ann Transl Med (2016)

RAD6 promotes chemoresistance in ovarian cancer

af Clark, David W., Mani, Chinnadurai, Palle, Komaraiah
Udgivet i Mol Cell Oncol (2017)

DNA repair fidelity in stem cell maintenance, health, and disease

af Mani, Chinnadurai, Reddy, P. Hemachandra, Palle, Komaraiah
Udgivet i Biochim Biophys Acta Mol Basis Dis (2019)

Aberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and Chemoresistance

af Palle, Komaraiah, Mani, Chinnadurai, Tripathi, Kaushlendra, Athar, Mohammad
Udgivet i Cancers (Basel) (2015)

Rad18 is required for functional interactions between FANCD2, BRCA2, and Rad51 to repair DNA topoisomerase 1-poisons induced lesions and promote fork recovery

af Tripathi, Kaushlendra, Mani, Chinnadurai, Clark, David W, Palle, Komaraiah
Udgivet i Oncotarget (2016)

FANCJ protein is important for the stability of FANCD2/FANCI proteins and protects them from proteasome and caspase-3 dependent degradation

af Clark, David W., Tripathi, Kaushlendra, Dorsman, Josephine C., Palle, Komaraiah
Udgivet i Oncotarget (2015)

Oxidative Stress in Metabolic Disorders: Pathogenesis, Prevention, and Therapeutics

af Yadav, Umesh C. S., Rani, Vibha, Deep, Gagan, Singh, Rakesh K., Palle, Komaraiah
Udgivet i Oxid Med Cell Longev (2016)

Synthesis and in vitro anticancer evaluation of some 4,6-diamino-1,3,5-triazine-2-carbohydrazides as Rad6 ubiquitin conjugating enzyme inhibitors

af Kothayer, Hend, Spencer, Sebastian M., Tripathi, Kaushlendra, Westwell, Andrew D., Palle, Komaraiah
Udgivet i Bioorg Med Chem Lett (2016)

Thymineless Death by the Fluoropyrimidine Polymer F10 Involves Replication Fork Collapse and Is Enhanced by Chk1 Inhibition

af Mani, Chinnadurai, Pai, Sachin, Papke, Cinta Maria, Palle, Komaraiah, Gmeiner, William H.
Udgivet i Neoplasia (2018)

Synthesis, anti-angiogenic and DNA cleavage studies of novel N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)piperidine-4-carboxamide derivatives

af Kambappa, Vinaya, Chandrashekara, G. K., Rekha, N. D., Shivaramu, Prasanna D., Palle, Komaraiah
Udgivet i Chem Cent J (2017)

Prexasertib treatment induces homologous recombination deficiency and synergizes with olaparib in triple-negative breast cancer cells

af Mani, Chinnadurai, Jonnalagadda, Shirisha, Lingareddy, Jojireddy, Awasthi, Sanjay, Gmeiner, William H., Palle, Komaraiah
Udgivet i Breast Cancer Res (2019)

Rad18-mediated Translesion Synthesis of Bulky DNA Adducts Is Coupled to Activation of the Fanconi Anemia DNA Repair Pathway

af Song, Ihn Young, Palle, Komaraiah, Gurkar, Aditi, Tateishi, Satoshi, Kupfer, Gary M., Vaziri, Cyrus
Udgivet 2010

Disulfide Cross-links Reveal Conserved Features of DNA Topoisomerase I Architecture and a Role for the N Terminus in Clamp Closure

af Palle, Komaraiah, Pattarello, Luca, van der Merwe, Marié, Losasso, Carmen, Benedetti, Piero, Bjornsti, Mary-Ann
Udgivet 2008

Sex Differences in Cardiovascular Disease and Cognitive Dysfunction in Rural West Elderly Texans

af Khan, Hafiz, Rafiq, Aamrin, Palle, Komaraiah, Faysel, Mohammad, Gabbidon, Kemesha, Chowdhury, Mohammed, Reddy, P. Hemachandra
Udgivet i J Alzheimers Dis Rep (2021)

The Multifunctional Protein PACS-1 is Required for HDAC2 and HDAC3 Dependent Chromatin Maturation and Genomic Stability

af Mani, Chinnadurai, Tripathi, Kaushlendra, Luan, Shan, Clark, David W., Andrews, Joel F., Vindigni, Alessandro, Thomas, Gary, Palle, Komaraiah
Udgivet i Oncogene (2020)

Single-molecule observations of topotecan-mediated TopIB activity at a unique DNA sequence

af Koster, Daniel A., Czerwinski, Fabian, Halby, Ludovic, Crut, Aurélien, Vekhoff, Pierre, Palle, Komaraiah, Arimondo, Paola B., Dekker, Nynke H.
Udgivet 2008

c-Jun N-terminal kinase–mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks

af Barkley, Laura R., Palle, Komaraiah, Durando, Michael, Day, Tovah A., Gurkar, Aditi, Kakusho, Naoko, Li, Jianying, Masai, Hisao, Vaziri, Cyrus
Udgivet 2012

Gli1 Protein Regulates the S-phase Checkpoint in Tumor Cells via Bid Protein, and Its Inhibition Sensitizes to DNA Topoisomerase 1 Inhibitors

af Tripathi, Kaushlendra, Mani, Chinnadurai, Barnett, Reagan, Nalluri, Sriram, Bachaboina, Lavanya, Rocconi, Rodney P., Athar, Mohammed, Owen, Laurie B., Palle, Komaraiah
Udgivet i J Biol Chem (2014)

GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis

af Srivastava, Ritesh K., Kaylani, Samer Zaid, Edrees, Nayf, Li, Changzhao, Talwelkar, Sarang S., Xu, Jianmin, Palle, Komaraiah, Pressey, Joseph G., Athar, Mohammad
Udgivet i Oncotarget (2014)