লোডিং...
Gli1 Protein Regulates the S-phase Checkpoint in Tumor Cells via Bid Protein, and Its Inhibition Sensitizes to DNA Topoisomerase 1 Inhibitors
Aberrant expression of hedgehog molecules, particularly Gli1, is common in cancers of many tissues and is responsible for their aggressive behavior and chemoresistance. Here we demonstrate a novel and tumor-specific role for aberrant Gli1 in the regulation of the S-phase checkpoint that suppresses r...
সংরক্ষণ করুন:
| প্রকাশিত: | J Biol Chem |
|---|---|
| প্রধান লেখক: | , , , , , , , , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
American Society for Biochemistry and Molecular Biology
2014
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4223349/ https://ncbi.nlm.nih.gov/pubmed/25253693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.606483 |
| ট্যাগগুলো: |
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