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Egfl7 promotes tumor escape from immunity

Egfl7 is an endothelial-specific gene which expression is deregulated in human cancers. We showed that Egfl7 promotes tumor escape from immunity by downregulating the expression of leukocyte adhesion molecules in endothelial cells, thus repressing immune cell extravasation into tumors.

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pinte, Sébastien, Soncin, Fabrice
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382845/
https://ncbi.nlm.nih.gov/pubmed/22737620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.18964
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