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Egfl7 promotes tumor escape from immunity

Egfl7 is an endothelial-specific gene which expression is deregulated in human cancers. We showed that Egfl7 promotes tumor escape from immunity by downregulating the expression of leukocyte adhesion molecules in endothelial cells, thus repressing immune cell extravasation into tumors.

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pinte, Sébastien, Soncin, Fabrice
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382845/
https://ncbi.nlm.nih.gov/pubmed/22737620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.18964
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