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Antigen shedding into the circulation contributes to tumor immune escape

Tumors employ various mechanisms to escape elimination by the immune system. In addition to the local induction of immunosuppressive cell types such as regulatory T cells or myeloid derived suppressor cells, tumor antigen shedding into the circulation may suppress antitumor CD8(+) T-cell function vi...

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Detalhes bibliográficos
Main Authors: Höchst, Bastian, Diehl, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525623/
https://ncbi.nlm.nih.gov/pubmed/23264914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21514
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