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Structural Insights of tBid, the Caspase-8-activated Bid, and Its BH(3) Domain
The Bcl-2 family proteins regulate mitochondria-mediated apoptosis through intricate molecular mechanisms. One of the pro-apoptotic proteins, tBid, can induce apoptosis by promoting Bax activation, Bax homo-oligomerization, and mitochondrial outer membrane permeabilization. Association of tBid on th...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3861634/ https://ncbi.nlm.nih.gov/pubmed/24158446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.503680 |
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