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Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein.

In response to various apoptotic stimuli, Bax, a pro-apoptotic member of the Bcl-2 family, is oligomerized and permeabilizes the mitochondrial outer membrane to apoptogenic factors, including cytochrome c. Bax oligomerization can also be induced by incubating isolated mitochondria containing endogen...

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Bibliografski detalji
Glavni autori: Roucou, Xavier, Montessuit, Sylvie, Antonsson, Bruno, Martinou, Jean-Claude
Format: Artigo
Jezik:Inglês
Izdano: 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223025/
https://ncbi.nlm.nih.gov/pubmed/12193163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020972
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