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Bid induces cytochrome c-impermeable Bax channels in liposomes.

Bax is a proapoptotic member of the Bcl-2 family of proteins. The Bax protein is dormant in the cytosol of normal cells and is activated upon induction of apoptosis. In apoptotic cells, Bax gets translocated to mitochondria, inserts into the outer membrane, oligomerizes and triggers the release of c...

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Hlavní autoři: Roucou, Xavier, Rostovtseva, Tatiana, Montessuit, Sylvie, Martinou, Jean-Claude, Antonsson, Bruno
Médium: Artigo
Jazyk:Inglês
Vydáno: 2002
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222507/
https://ncbi.nlm.nih.gov/pubmed/11964155
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