DNA demethylating agents synergize with oncolytic HSV1 against malignant gliomas

PURPOSE: Oncolytic viruses (OV) based on herpes simplex virus type 1 (HSV1) are being utilized in clinical trials for a variety of cancers. The OV, rQNestin34.5, utilizes a nestin promoter/enhancer to selectively drive robust viral replication in malignant glioma cells. We have discovered that this...

詳細記述

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書誌詳細
主要な著者: Okemoto, Kazuo, Kasai, Kazue, Wagner, Benjamin, Haseley, Amy, Meisen, Hans, Bolyard, Chelsea, Mo, Xiaokui, Wehr, Allison, Lehman, Amy, Fernandez, Soledad, Kaur, Balveen, Chiocca, E. Antonio
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860592/
https://ncbi.nlm.nih.gov/pubmed/24056786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3588
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