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A Trifluoromethyl Analogue of Celecoxib Exerts Beneficial Effects in Neuroinflammation
Celecoxib is a selective cyclooxygenase-2 (COX2) inhibitor. We have previously shown that celecoxib inhibits experimental autoimmune encephalomyelitis (EAE) in COX-2-deficient mice, suggestive for a mode of action involving COX2-independent pathways. In the present study, we tested the effect of a t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3859644/ https://ncbi.nlm.nih.gov/pubmed/24349442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083119 |
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