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The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells
OCH, a sphingosine-truncated analog of α-galactosylceramide (αGC), is a potential therapeutic reagent for a variety of Th1-mediated autoimmune diseases through its selective induction of Th2 cytokines from natural killer T (NKT) cells. We demonstrate here that the NKT cell production of IFN-γ is mor...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419488/ https://ncbi.nlm.nih.gov/pubmed/15173890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420862 |
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