A novel glycolipid antigen for NKT cells that preferentially induces IFN-γ production

Here we characterize a novel Ag for invariant natural killer T-cells (iNKT cells) capable of producing an especially robust Th1 response. This glycosphingolipid (GSL), DB06-1, is similar in chemical structure to the well-studied α-galactosylceramide (αGalCer), the only change being in a single atom,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Birkholz, Alysia M., Girardi, Enrico, Wingender, Gerhard, Khurana, Archana, Wang, Jing, Zhao, Meng, Zahner, Sonja, Illarionov, Petr A., Wen, Xiangshu, Li, Michelle, Yuan, Weiming, Porcelli, Steven A., Besra, Gurdyal S., Zajonc, Dirk M., Kronenberg, Mitchell
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506857/
https://ncbi.nlm.nih.gov/pubmed/26078271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500070
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