A novel glycolipid antigen for NKT cells that preferentially induces IFN-γ production

Here we characterize a novel Ag for invariant natural killer T-cells (iNKT cells) capable of producing an especially robust Th1 response. This glycosphingolipid (GSL), DB06-1, is similar in chemical structure to the well-studied α-galactosylceramide (αGalCer), the only change being in a single atom,...

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Publicado no:J Immunol
Main Authors: Birkholz, Alysia M., Girardi, Enrico, Wingender, Gerhard, Khurana, Archana, Wang, Jing, Zhao, Meng, Zahner, Sonja, Illarionov, Petr A., Wen, Xiangshu, Li, Michelle, Yuan, Weiming, Porcelli, Steven A., Besra, Gurdyal S., Zajonc, Dirk M., Kronenberg, Mitchell
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506857/
https://ncbi.nlm.nih.gov/pubmed/26078271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500070
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