A Trifluoromethyl Analogue of Celecoxib Exerts Beneficial Effects in Neuroinflammation

Celecoxib is a selective cyclooxygenase-2 (COX2) inhibitor. We have previously shown that celecoxib inhibits experimental autoimmune encephalomyelitis (EAE) in COX-2-deficient mice, suggestive for a mode of action involving COX2-independent pathways. In the present study, we tested the effect of a t...

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Hlavní autoři: Di Penta, Alessandra, Chiba, Asako, Alloza, Iraide, Wyssenbach, Ane, Yamamura, Takashi, Villoslada, Pablo, Miyake, Sachiko, Vandenbroeck, Koen
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859644/
https://ncbi.nlm.nih.gov/pubmed/24349442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083119
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