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Inhibition of mitochondrial fragmentation diminishes Huntington’s disease–associated neurodegeneration
Huntington’s disease (HD) is the result of expression of a mutated Huntingtin protein (mtHtt), and is associated with a variety of cellular dysfunctions including excessive mitochondrial fission. Here, we tested whether inhibition of excessive mitochondrial fission prevents mtHtt-induced pathology....
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3859413/ https://ncbi.nlm.nih.gov/pubmed/24231356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70911 |
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