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A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity

Excessive mitochondrial fission is associated with the pathology of a number of neurodegenerative diseases. Therefore, inhibitors of aberrant mitochondrial fission could provide important research tools in addition to potential leads for drug development. Using a rational approach, we designed a nov...

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Bibliografski detalji
Glavni autori: Qi, Xin, Qvit, Nir, Su, Yu-Chin, Mochly-Rosen, Daria
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619809/
https://ncbi.nlm.nih.gov/pubmed/23239023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.114439
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