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A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity
Excessive mitochondrial fission is associated with the pathology of a number of neurodegenerative diseases. Therefore, inhibitors of aberrant mitochondrial fission could provide important research tools in addition to potential leads for drug development. Using a rational approach, we designed a nov...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Company of Biologists
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3619809/ https://ncbi.nlm.nih.gov/pubmed/23239023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.114439 |
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